Yields from solid acids are not as great, but odours are detectable and distinctive. Allow the mixture to cool to room temperature. Ester Preparation Lab Introduction: Included with the report is the MSDS data sheet.
The solubility of aspirin in water increases as the temperature increases. Place the 25 mL Erlenmeyer flask containing the product and ethyl acetate directly on the hot plate at 50 degrees Celsius. The reason for this is due to an increase in kinetic energy.
Make sure while heating, in equal intervals agitate the mixture carefully to ensure the sulphuric acid is dispersed. Record the color observations. Next a phenol test was performed on the crude aspirin product, the purified aspirin product, and salicylic acid as a control.
Test tube C, which contained salicylic acid, had an extreme change in color and turned dark purple. Then place the beaker into a warm and dry place and leave for 24 hours. Therefore precautions to chemicals such as Acetylsalicylic acid were taken as it is irritating to the eyes.
A pure compound has a specific range in which it melts and it is normally a fairly small range. The aspirin product that was collected still contained some impurities. Salicylic acid was then industrialized for medicinal use, but soon after industrialization it was found that salicylic acid was extremely limited as a treatment because of the acidic properties that cause severe irritation in the digestive tract.
Record the temperature range that the sample melts within. Leave the mL Erlenmeyer flask that contains the mixture in its ice bath and allow it to cool for an extra 5 minutes.
Write word equations for each reaction, and for advanced students chemical equations using structural formulae. Turn the capillary tube back to the upright position.
The mass of the purified aspirin product was 0. Then carefully filter the product using the filter paper and filtering equipment such as the vacuumed container.
IUPAC names ester from two words: Look carefully at the aspirin in the small test tube. The crystal product will be stuck at the top of the capillary tube. The information we gather will allow us to determine the percent yield of the crude aspirin product and of the purified aspirin product.
active component, salicylic acid (SA), can, however, cause stomach upset because its acidity (pK a = ) can be higher than the pH of the human stomach (pH ~ 4 after digestion is complete). Figure 1. Salicylic Acid Salicylic acid is a diprotic organic acid with two acidic functional groups: a carboxylic acid and a phenol.
· The purpose of this experiment was to synthesize acetylsalicylic acid via an esterification reaction between salicylic acid and acetic anhydride.
The product was recrystallized using 95% douglasishere.com://douglasishere.com Ester Preparation Lab Introduction: An ester is an organic compound which is created from a reaction between an acid and an alcohol, usually with the loss of water. The goal of this experiment was to synthesize aspirin.
In this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic anhydride. In the reaction the hydroxyl group on the benzene ring in salicylic acid reacted with acetic anhydride to form an ester functional group.
This method of forming acetylsalicylic acid. · Salicylic acid has an -OH group (an alcohol) and a carboxyl group -COOH (an organic acid).
The acid portion of the molecule is one of the factors that cause irritation in the stomach. In addition to irritation caused by acidity, aspirin causes stomach irritation by inhibiting the production of prostaglandins, hormones responsible for slowing douglasishere.com · an esterification reaction between salicylic acid and acetic anhydride.
This type of interaction involves a reaction of a carboxylic acid with an alcohol in order to form a carboxylate ester 2,douglasishere.comAn analysis of a laboratory esterification experiment on salicylic acid